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TitleIdentification of SRC3/AIB1 as a Preferred Coactivator for Hormone-activated Androgen Receptor.
Journal, issue, pagesJ. Biol. Chem., Vol. 285, Page 9161-9171, Year 2010
Publish dateDec 18, 2009 (structure data deposition date)
AuthorsZhou, X.E. / Suino-Powell, K.M. / Li, J. / He, Y. / Mackeigan, J.P. / Melcher, K. / Yong, E.L. / Xu, H.E.
External linksJ. Biol. Chem. / PubMed:20086010
MethodsX-ray diffraction
Resolution1.55 - 2 Å
Structure data

PDB-3l3x:
Crystal structure of DHT-bound androgen receptor in complex with the first motif of steroid receptor coactivator 3
Method: X-RAY DIFFRACTION / Resolution: 1.55 Å

PDB-3l3z:
Crystal structure of DHT-bound androgen receptor in complex with the third motif of steroid receptor coactivator 3
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-DHT:
5-ALPHA-DIHYDROTESTOSTERONE / hormone*YM

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsPROTEIN BINDING / androgen receptor / ligand binding domain / steroid receptor coactivator 3 / 5-alpha-dihydrotestosterone (DHT) / prostate cancer

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