Database of articles cited by EMDB/PDB/SASBDB data

Keywords
Structure methods	All X-ray diffraction NMR electron microscopy small angle scattering neutron diffraction fiber diffraction powder diffraction infrared spectroscopy EPR fluorescence transfer theoretical model Hybrid
Author
Journal
IF	>30 >20 >10 >5 all

Title	Design, synthesis, and X-ray crystal structures of 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors.
Journal, issue, pages	Bioorg. Med. Chem., Vol. 17, Page 7324-7336, Year 2009
Publish date	Oct 5, 2009 (structure data deposition date)
Authors	Gangjee, A. / Li, W. / Lin, L. / Zeng, Y. / Ihnat, M. / Warnke, L.A. / Green, D.W. / Cody, V. / Pace, J. / Queener, S.F.
External links	Bioorg. Med. Chem. / PubMed:19748785
Methods	X-ray diffraction
Resolution	1.6 - 2.05 Å
Structure data	PDB-3k45: Alternate Binding Modes Observed for the E- and Z-isomers of 2,4-Diaminofuro[2,3d]pyrimidines as Ternary Complexes with NADPH and Mouse Dihydrofolate Reductase Method: X-RAY DIFFRACTION / Resolution: 1.6 Å PDB-3k47: Alternate Binding Modes Observed for the E- and Z-Isomers of 2,4-Diaminofuro[2,3-d]pyrimidines as Ternary Complexes with NADPH and Mouse Dihydrofolate Reductase Method: X-RAY DIFFRACTION / Resolution: 2.05 Å
Chemicals	ChemComp-NDP: NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE ChemComp-51P: 5-[(1Z)-2-(2-methoxyphenyl)prop-1-en-1-yl]furo[2,3-d]pyrimidine-2,4-diamine ChemComp-HOH: WATER ChemComp-D09: 5-[(1E)-2-(2-methoxyphenyl)prop-1-en-1-yl]furo[2,3-d]pyrimidine-2,4-diamine
Source	mus musculus (house mouse)
Keywords	OXIDOREDUCTASE / PROTEIN LIGAND COFACTOR TERNARY COMPLEX / NADP / ONE-CARBON METABOLISM / MOUSE DIHYDROFOLATE REDUCTASE COFACTOR LIGAND COMPLEX