+Search query
-Structure paper
Title | Di-substituted pyridinyl aminohydantoins as potent and highly selective human beta-secretase (BACE1) inhibitors. |
---|---|
Journal, issue, pages | Bioorg. Med. Chem., Vol. 18, Page 630-639, Year 2010 |
Publish date | Aug 11, 2009 (structure data deposition date) |
![]() | Malamas, M.S. / Barnes, K. / Johnson, M. / Hui, Y. / Zhou, P. / Turner, J. / Hu, Y. / Wagner, E. / Fan, K. / Chopra, R. ...Malamas, M.S. / Barnes, K. / Johnson, M. / Hui, Y. / Zhou, P. / Turner, J. / Hu, Y. / Wagner, E. / Fan, K. / Chopra, R. / Olland, A. / Bard, J. / Pangalos, M. / Reinhart, P. / Robichaud, A.J. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2 - 2.3 Å |
Structure data | ![]() PDB-3in3: ![]() PDB-3in4: |
Chemicals | ![]() ChemComp-472: ![]() ChemComp-HOH: ![]() ChemComp-BX2: |
Source |
|
![]() | ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() ![]() |