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Structure paper

TitleStructural basis for the sugar nucleotide and acyl-chain selectivity of Leptospira interrogans LpxA.
Journal, issue, pagesBiochemistry, Vol. 48, Page 6191-6201, Year 2009
Publish dateJun 10, 2009 (structure data deposition date)
AuthorsRobins, L.I. / Williams, A.H. / Raetz, C.R.
External linksBiochemistry / PubMed:19456129
MethodsX-ray diffraction
Resolution2.1 - 2.12 Å
Structure data

PDB-3hsq:
Structural Basis for the Sugar Nucleotide and Acyl Chain Selectivity of Leptospira interrogans LpxA
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-3i3a:
Structural Basis for the Sugar Nucleotide and Acyl Chain Selectivity of Leptospira interrogans LpxA
Method: X-RAY DIFFRACTION / Resolution: 2.12 Å

PDB-3i3x:
Structural Basis for the Sugar Nucleotide and Acyl Chain Selectivity of Leptospira interrogans LpxA
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-HOH:
WATER

ChemComp-S2N:
S-[2-({N-[(2R)-2-hydroxy-4-{[(S)-hydroxy(methoxy)phosphoryl]oxy}-3,3-dimethylbutanoyl]-beta-alanyl}amino)ethyl] (3R)-3-hydroxydodecanethioate

ChemComp-U22:
uridine-5'-diphosphate-3-N-(R-3-hydroxylauroyl)-N-acetyl-D-glucosamine

Source
  • leptospira interrogans (bacteria)
KeywordsTRANSFERASE / L.interrogans LPXA / LPXA / LPXA crystal structure / Acyltransferase / Lipid A biosynthesis / Lipid synthesis / Leptospira Interrogans / Leptospira interrogans complex / Leptospira Interrogans LpxA / L. interrogans LpxA / L. interrogans LpxA product complex

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