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Structure paper

TitleStructure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 91, Page 3911-3915, Year 1994
Publish dateJul 25, 1994 (structure data deposition date)
AuthorsSmerdon, S.J. / Jager, J. / Wang, J. / Kohlstaedt, L.A. / Chirino, A.J. / Friedman, J.M. / Rice, P.A. / Steitz, T.A.
External linksProc. Natl. Acad. Sci. Usa / PubMed:7513427
MethodsX-ray diffraction
Resolution2.9 Å
Structure data

PDB-3hvt:
STRUCTURAL BASIS OF ASYMMETRY IN THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE HETERODIMER
Method: X-RAY DIFFRACTION / Resolution: 2.9 Å

Chemicals

ChemComp-NVP:
11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE / medication, antiretroviral*YM

Source
  • human immunodeficiency virus 1
KeywordsNUCLEOTIDYLTRANSFERASE

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