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Structure paper

Titlep38alpha MAP kinase C-terminal domain binding pocket characterized by crystallographic and computational analyses.
Journal, issue, pagesJ. Mol. Biol., Vol. 391, Page 1-11, Year 2009
Publish dateJun 15, 2009 (structure data deposition date)
AuthorsPerry, J.J. / Harris, R.M. / Moiani, D. / Olson, A.J. / Tainer, J.A.
External linksJ. Mol. Biol. / PubMed:19501598
MethodsX-ray diffraction
Resolution2.1 Å
Structure data

PDB-3hvc:
Crystal structure of human p38alpha MAP kinase
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-GG5:
4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / MAP KINASE / SERINE/THREONINE-PROTEIN KINASE / P38 / ISOFORM-2 / Alternative splicing / ATP-binding / Cytoplasm / Kinase / Nucleotide-binding / Nucleus / Phosphoprotein / Polymorphism

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