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Structure paper

TitleCrystal Structures of TbCatB and rhodesain, potential chemotherapeutic targets and major cysteine proteases of Trypanosoma brucei
Journal, issue, pagesPlos Negl Trop Dis, Vol. 4, Page e701-e701, Year 2010
Publish dateMay 15, 2009 (structure data deposition date)
AuthorsKerr, I.D. / Wu, P. / Marion-Tsukamaki, R. / Mackey, Z.B. / Brinen, L.S.
External linksPlos Negl Trop Dis / PubMed:20544024
MethodsX-ray diffraction
Resolution1.6 Å
Structure data

PDB-3hhi:
Crystal Structure of Cathepsin B from T. brucei in complex with CA074
Method: X-RAY DIFFRACTION / Resolution: 1.6 Å

Chemicals

ChemComp-074:
[PROPYLAMINO-3-HYDROXY-BUTAN-1,4-DIONYL]-ISOLEUCYL-PROLINE

ChemComp-TRS:
2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL / pH buffer*YM

ChemComp-GOL:
GLYCEROL

ChemComp-MG:
Unknown entry

ChemComp-LI:
Unknown entry

ChemComp-HOH:
WATER

Source
  • trypanosoma brucei (eukaryote)
KeywordsHYDROLASE / cysteine protease / occluding loop / Protease / Thiol protease

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