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-Structure paper
Title | Principles of ligand binding within a completely buried cavity in HIF2alpha PAS-B |
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Journal, issue, pages | J. Am. Chem. Soc., Vol. 131, Page 17647-17654, Year 2009 |
Publish date | Apr 28, 2009 (structure data deposition date) |
![]() | Key, J. / Scheuermann, T.H. / Anderson, P.C. / Daggett, V. / Gardner, K.H. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 1.5 - 1.65 Å |
Structure data | ![]() PDB-3h7w: ![]() PDB-3h82: |
Chemicals | ![]() ChemComp-018: ![]() ChemComp-HOH: ![]() ChemComp-020: |
Source |
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![]() | TRANSCRIPTION / PAS domain / heterodimer / protein ligand complex. / Activator / Angiogenesis / Congenital erythrocytosis / Developmental protein / Differentiation / Disease mutation / DNA-binding / Hydroxylation / Nucleus / Phosphoprotein / Transcription regulation / Ubl conjugation / Alternative splicing / Polymorphism |