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-Structure paper
Title | Structure of aldehyde reductase holoenzyme in complex with the potent aldose reductase inhibitor fidarestat: implications for inhibitor binding and selectivity |
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Journal, issue, pages | J. Med. Chem., Vol. 48, Page 5536-5542, Year 2005 |
Publish date | Apr 20, 2009 (structure data deposition date) |
Authors | El-Kabbani, O. / Carbone, V. / Darmanin, C. / Oka, M. / Mitschler, A. / Podjarny, A. / Schulze-Briese, C. / Chung, R.P. |
External links | J. Med. Chem. / PubMed:16107153 |
Methods | X-ray diffraction |
Resolution | 1.85 Å |
Structure data | PDB-3h4g: |
Chemicals | ChemComp-SO4: ChemComp-NAP: ChemComp-FID: ChemComp-HOH: |
Source |
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Keywords | OXIDOREDUCTASE / TIM BARREL / ALDO-KETO REDUCTASE / TERNARY COMPLEX / NADP |