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-Structure paper
Title | Structures of Pathogenic SOD1 Mutants H80R and D124V: Disrupted Zinc-binding and Compromised Post-translational Modification by the Copper Chaperone CCS |
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Journal, issue, pages | To be Published |
Publish date | Apr 14, 2009 (structure data deposition date) |
Authors | Seetharaman, S.V. / Winkler, D.D. / Taylor, A.B. / Cao, X. / Whitson, L.J. / Doucette, P.A. / Valentine, J.S. / Carroll, M.C. / Culotta, V.C. / Hart, P.J. |
External links | Search PubMed |
Methods | X-ray diffraction |
Resolution | 1.55 - 1.85 Å |
Structure data | PDB-3h2p: PDB-3h2q: |
Chemicals | ChemComp-ZN: ChemComp-MLI: ChemComp-ACE: ChemComp-HOH: ChemComp-SO4: |
Source |
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Keywords | OXIDOREDUCTASE / human cu / zn superoxide dismutase / antioxidant / metal-binding / copper / zinc / amyotrophic lateral sclerosis / disease mutation / Acetylation / Cytoplasm / Disulfide bond / Phosphoprotein / Ubl conjugation |