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Structure paper

TitleBerberine bridge enzyme catalyzes the six electron oxidation of (S)-reticuline to dehydroscoulerine.
Journal, issue, pagesPhytochemistry, Vol. 70, Page 1092-1097, Year 2009
Publish dateMar 27, 2009 (structure data deposition date)
AuthorsWinkler, A. / Puhl, M. / Weber, H. / Kutchan, T.M. / Gruber, K. / Macheroux, P.
External linksPhytochemistry / PubMed:19570558
MethodsX-ray diffraction
Resolution1.63 Å
Structure data

PDB-3gsy:
Structure of berberine bridge enzyme in complex with dehydroscoulerine
Method: X-RAY DIFFRACTION / Resolution: 1.63 Å

Chemicals

ChemComp-FAD:
FLAVIN-ADENINE DINUCLEOTIDE / FAD*YM

ChemComp-DEH:
2,9-dihydroxy-3,10-dimethoxy-5,6-dihydroisoquino[3,2-a]isoquinolinium

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • eschscholzia californica (California poppy)
KeywordsOXIDOREDUCTASE / complex with dehydroscoulerine / bicovalent flavinylation / N-glycosylation / p-cresol methyl hydroxylase superfamily / Alkaloid metabolism / Cytoplasmic vesicle / FAD / Flavoprotein / Glycoprotein

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