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-Structure paper
Title | Synthetic and structural studies on syringolin A and B reveal critical determinants of selectivity and potency of proteasome inhibition |
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Journal, issue, pages | Proc. Natl. Acad. Sci. USA, Vol. 106, Page 6507-6512, Year 2009 |
Publish date | Mar 23, 2009 (structure data deposition date) |
![]() | Clerc, J. / Groll, M. / Illich, D.J. / Bachmann, A.S. / Huber, R. / Schellenberg, B. / Dudler, R. / Kaiser, M. |
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Methods | X-ray diffraction |
Resolution | 2.7 Å |
Structure data | ![]() PDB-3gpj: |
Chemicals | ![]() ChemComp-SY2: ![]() ChemComp-HOH: |
Source |
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![]() | HYDROLASE / Proteasome / virulence / ubiquitin / cancer therapy / immunology / Cytoplasm / Nucleus / Phosphoprotein / Protease / Threonine protease / Isopeptide bond / Ubl conjugation / Zymogen |