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TitleCrystal Structure of Human Mitogen Activated Protein Kinase 11 (p38 beta) in complex with Nilotinib
Journal, issue, pagesTo be Published
Publish dateMar 20, 2009 (structure data deposition date)
AuthorsFilippakopoulos, P. / Barr, A. / Fedorov, O. / Keates, T. / Soundararajan, M. / Elkins, J. / Salah, E. / Burgess-Brown, N. / Ugochukwu, E. / Pike, A.C.W. ...Filippakopoulos, P. / Barr, A. / Fedorov, O. / Keates, T. / Soundararajan, M. / Elkins, J. / Salah, E. / Burgess-Brown, N. / Ugochukwu, E. / Pike, A.C.W. / Muniz, J. / Roos, A. / Chaikuad, A. / von Delft, F. / Arrowsmith, C.H. / Edwards, A.M. / Weigelt, J. / Bountra, C. / Knapp, S. / Structural Genomics Consortium (SGC)
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-3gp0:
Crystal Structure of Human Mitogen Activated Protein Kinase 11 (p38 beta) in complex with Nilotinib
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-NIL:
Nilotinib / medication, anticancer*YM

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-CL:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTransferase/Transferase Inhibitor / mitogen-activated protein kinase 11 / P38B / P38BETA / PRKM11 / SAPK2 / SAPK2B / stress-activated protein kinase-2 / structural genomics consortium / SGC / ATP-binding / Kinase / Nucleotide-binding / Phosphoprotein / Serine/threonine-protein kinase / Transferase / Transferase-Transferase Inhibitor COMPLEX

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