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TitleAdaptive ligand binding by the purine riboswitch in the recognition of Guanine and adenine analogs.
Journal, issue, pagesStructure, Vol. 17, Page 857-868, Year 2009
Publish dateDec 27, 2008 (structure data deposition date)
AuthorsGilbert, S.D. / Reyes, F.E. / Edwards, A.L. / Batey, R.T.
External linksStructure / PubMed:19523903
MethodsX-ray diffraction
Resolution1.7 - 2.4 Å
Structure data

PDB-3fo4:
Crystal structure of guanine riboswitch C74U mutant bound to 6-chloroguanine
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-3fo6:
Crystal structure of guanine riboswitch bound to 6-O-methylguanine
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-3g4m:
Crystal structure of guanine riboswitch bound to 2-aminopurine
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

PDB-3gao:
Crystal structure of the guanine riboswitch bound to xanthine.
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-3ger:
Guanine riboswitch bound to 6-chloroguanine
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

PDB-3ges:
Crystal structure of the guanine riboswitch C74U mutant bound to 6-O-methylguanine
Method: X-RAY DIFFRACTION / Resolution: 2.15 Å

PDB-3gog:
Guanine riboswitch A21G,U75C mutant bound to 6-chloroguanine
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

PDB-3got:
Guanine riboswitch C74U mutant bound to 2-fluoroadenine.
Method: X-RAY DIFFRACTION / Resolution: 1.95 Å

Chemicals

ChemComp-6GU:
6-chloroguanine

ChemComp-ACT:
ACETATE ION

ChemComp-NCO:
COBALT HEXAMMINE(III)

ChemComp-HOH:
WATER

ChemComp-6GO:
6-O-methylguanine

ChemComp-2BP:
9H-purin-2-amine

ChemComp-XAN:
XANTHINE

ChemComp-MG:
Unknown entry

ChemComp-A2F:
2-fluoroadenine

KeywordsRNA / mRNA / riboswitch / 6-chloroguanine / adenine / RNA-ligand complex / double helix / three-way junction / guanine / 6-O-methylguanine / 2-aminopurine / base-triple. / xanthine / RNA_ligand complex / base triple

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