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-Structure paper
Title | Structure-based design of 7-azaindole-pyrrolidine amides as inhibitors of 11 beta-hydroxysteroid dehydrogenase type I. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 22, Page 5909-5914, Year 2012 |
Publish date | Mar 13, 2009 (structure data deposition date) |
![]() | Valeur, E. / Christmann-Franck, S. / Lepifre, F. / Carniato, D. / Cravo, D. / Charon, C. / Bozec, S. / Musil, D. / Hillertz, P. / Doare, L. ...Valeur, E. / Christmann-Franck, S. / Lepifre, F. / Carniato, D. / Cravo, D. / Charon, C. / Bozec, S. / Musil, D. / Hillertz, P. / Doare, L. / Schmidlin, F. / Lecomte, M. / Schultz, M. / Roche, D. |
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Methods | X-ray diffraction |
Resolution | 2.28 Å |
Structure data | ![]() PDB-3gmd: |
Chemicals | ![]() ChemComp-NDP: ![]() ChemComp-2M3: ![]() ChemComp-SO4: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE/OXIDOREDUCTASE INHIBITOR / ALPHA/BETA / Endoplasmic reticulum / Glycoprotein / Lipid metabolism / Membrane / NADP / Oxidoreductase / Signal-anchor / Steroid metabolism / Transmembrane / OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR COMPLEX |