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TitleCrystal structures of a therapeutic single chain antibody in complex with two drugs of abuse-Methamphetamine and 3,4-methylenedioxymethamphetamine.
Journal, issue, pagesProtein Sci., Vol. 18, Page 2336-2345, Year 2009
Publish dateMar 11, 2009 (structure data deposition date)
AuthorsCelikel, R. / Peterson, E.C. / Owens, S.M. / Varughese, K.I.
External linksProtein Sci. / PubMed:19760665
MethodsX-ray diffraction
Resolution1.9 - 2.4 Å
Structure data

PDB-3gkz:
Crystal structures of a therapeutic single chain antibody in complex methamphetamine
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

PDB-3gm0:
Anti-methamphetamine single chain Fv in complex with MDMA
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-B40:
(2S)-N-methyl-1-phenylpropan-2-amine

ChemComp-HOH:
WATER

ChemComp-B41:
(2S)-1-(1,3-benzodioxol-5-yl)-N-methylpropan-2-amine

Source
  • mus musculus (house mouse)
KeywordsIMMUNE SYSTEM / Therapeutic antibody / Methamphetamine / amphetamine / MDMA / IgG / anti-methamphetamine antibody / single chain Fv

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