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-Structure paper
Title | Nimotuzumab, an antitumor antibody that targets the epidermal growth factor receptor, blocks ligand binding while permitting the active receptor conformation |
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Journal, issue, pages | Cancer Res., Vol. 69, Page 5851-5859, Year 2009 |
Publish date | Mar 11, 2009 (structure data deposition date) |
![]() | Talavera, A. / Friemann, R. / Gomez-Puerta, S. / Martinez-Fleites, C. / Garrido, G. / Rabasa, A. / Lopez-Requena, A. / Pupo, A. / Johansen, R.F. / Sanchez, O. ...Talavera, A. / Friemann, R. / Gomez-Puerta, S. / Martinez-Fleites, C. / Garrido, G. / Rabasa, A. / Lopez-Requena, A. / Pupo, A. / Johansen, R.F. / Sanchez, O. / Krengel, U. / Moreno, E. |
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Methods | X-ray diffraction |
Resolution | 2.5 Å |
Structure data | ![]() PDB-3gkw: |
Chemicals | ![]() ChemComp-PEG: ![]() ChemComp-1PE: ![]() ChemComp-HOH: |
Source |
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![]() | IMMUNE SYSTEM / ANTITUMOR PROTEIN / Immunoglobulin fold / Displaced strictly conserved TRP 103 following Kabat numbering |