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-Structure paper
Title | Mode of binding of the tuberculosis prodrug isoniazid to heme peroxidases: binding studies and crystal structure of bovine lactoperoxidase with isoniazid at 2.7 A resolution. |
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Journal, issue, pages | J. Biol. Chem., Vol. 285, Page 1569-1576, Year 2010 |
Publish date | Feb 21, 2009 (structure data deposition date) |
![]() | Singh, A.K. / Kumar, R.P. / Pandey, N. / Singh, N. / Sinha, M. / Bhushan, A. / Kaur, P. / Sharma, S. / Singh, T.P. |
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Methods | X-ray diffraction |
Resolution | 2.5 - 2.7 Å |
Structure data | ![]() PDB-3gc1: ![]() PDB-3i6n: |
Chemicals | ![]() ChemComp-HEM: ![]() ChemComp-CA: ![]() ChemComp-SCN: ![]() ChemComp-IOD: ![]() ChemComp-HOH: ![]() ChemComp-ISZ: |
Source |
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![]() | OXIDOREDUCTASE / Peroxidase / Heme / Antibiotic / Antimicrobial / Cleavage on pair of basic residues / Glycoprotein / Hydrogen peroxide / Iron / Metal-binding / Secreted / Antimicrobial activity / Oxidation / Disulfide bond |