+Search query
-Structure paper
Title | Structure of a mutant human purine nucleoside phosphorylase with the prodrug, 2-fluoro-2'-deoxyadenosine and the cytotoxic drug, 2-fluoroadenine. |
---|---|
Journal, issue, pages | Protein Sci., Vol. 18, Page 1107-1114, Year 2009 |
Publish date | Feb 19, 2009 (structure data deposition date) |
Authors | Afshar, S. / Sawaya, M.R. / Morrison, S.L. |
External links | Protein Sci. / PubMed:19388075 |
Methods | X-ray diffraction |
Resolution | 2.3 - 2.52 Å |
Structure data | PDB-3gb9: PDB-3ggs: |
Chemicals | ChemComp-A2F: ChemComp-SO4: ChemComp-GOL: ChemComp-HOH: ChemComp-2FD: |
Source |
|
Keywords | TRANSFERASE / Enzyme-product complex / Disease mutation / Glycosyltransferase / enzyme-prodrug complex |