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-Structure paper
Title | 2-{3-[4-(Alkylsulfinyl)phenyl]-1-benzofuran-5-yl}-5-methyl-1,3,4-oxadiazole derivatives as novel inhibitors of glycogen synthase kinase-3beta with good brain permeability. |
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Journal, issue, pages | J. Med. Chem., Vol. 52, Page 6270-6286, Year 2009 |
Publish date | Feb 18, 2009 (structure data deposition date) |
![]() | Saitoh, M. / Kunitomo, J. / Kimura, E. / Iwashita, H. / Uno, Y. / Onishi, T. / Uchiyama, N. / Kawamoto, T. / Tanaka, T. / Mol, C.D. ...Saitoh, M. / Kunitomo, J. / Kimura, E. / Iwashita, H. / Uno, Y. / Onishi, T. / Uchiyama, N. / Kawamoto, T. / Tanaka, T. / Mol, C.D. / Dougan, D.R. / Textor, G.P. / Snell, G.P. / Takizawa, M. / Itoh, F. / Kori, M. |
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Methods | X-ray diffraction |
Resolution | 2.4 Å |
Structure data | ![]() PDB-3gb2: |
Chemicals | ![]() ChemComp-G3B: ![]() ChemComp-HOH: |
Source |
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![]() | TRANSFERASE / protein kinase / inhibitor / complex / ATP-binding / Kinase / Nucleotide-binding / Phosphoprotein / Serine/threonine-protein kinase / Wnt signaling pathway / CDM |