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TitleOptical 2-benzyl-5-hydroxy4oxopentanoic acids against carboxypeptidase A: Synthesis, kinetic evaluation and X-ray crystallographic study
Journal, issue, pagesCHIN. CHEM. LETT., Vol. 21, Page 159-162, Year 2010
Publish dateJan 16, 2009 (structure data deposition date)
AuthorsWang, S.F. / Jin, J.-Y. / Zeng, Z.H. / Tian, G.R.
External linksCHIN. CHEM. LETT. / Search PubMed
MethodsX-ray diffraction
Resolution1.85 Å
Structure data

PDB-3fvl:
Crystallogic studies on the Complex of Carboxypeptidase A with inhibitors using alpha-hydroxy ketone as zinc-binding group
Method: X-RAY DIFFRACTION / Resolution: 1.85 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-BHK:
(2R)-2-benzyl-5-hydroxy-4-oxopentanoic acid

ChemComp-HOH:
WATER

Source
  • bos taurus (domestic cattle)
KeywordsHYDROLASE / carboxypeptidase A / alpha-hydroxy ketone / inhibitor / Carboxypeptidase / Metal-binding / Metalloprotease / Polymorphism / Protease / Secreted / Zinc / Zymogen

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