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-Structure paper
| Title | N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte fatty-acid binding protein (A-FABP) inhibitors. |
|---|---|
| Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 19, Page 1745-1748, Year 2009 |
| Publish date | Jan 8, 2009 (structure data deposition date) |
Authors | Barf, T. / Lehmann, F. / Hammer, K. / Haile, S. / Axen, E. / Medina, C. / Uppenberg, J. / Svensson, S. / Rondahl, L. / Lundback, T. |
External links | Bioorg. Med. Chem. Lett. / PubMed:19217286 |
| Methods | X-ray diffraction |
| Resolution | 2.16 - 2.2 Å |
| Structure data | ![]() PDB-3fr2: ![]() PDB-3fr4: ![]() PDB-3fr5: |
| Chemicals | ![]() ChemComp-8CA: ![]() ChemComp-HOH: ![]() ChemComp-F8A: ![]() ChemComp-I4A: |
| Source |
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Keywords | LIPID BINDING PROTEIN / selective adipocyte Fatty-Acid Binding Protein (A-FABP) inhibitors / Cytoplasm / Lipid-binding / Nucleus / Phosphoprotein / Polymorphism / Transport |
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homo sapiens (human)
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