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TitleCrystal Structure of Human Haspin with an Isoquinoline ligand
Journal, issue, pagesTo be Published
Publish dateDec 21, 2008 (structure data deposition date)
AuthorsFilippakopoulos, P. / Eswaran, J. / Keates, T. / Burgess-Brown, N. / Fedorov, O. / Pike, A.C.W. / von Delft, F. / Arrowsmith, C.H. / Edwards, A.M. / Weigelt, J. ...Filippakopoulos, P. / Eswaran, J. / Keates, T. / Burgess-Brown, N. / Fedorov, O. / Pike, A.C.W. / von Delft, F. / Arrowsmith, C.H. / Edwards, A.M. / Weigelt, J. / Bountra, C. / Knapp, S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-3fmd:
Crystal Structure of Human Haspin with an Isoquinoline ligand
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-IQB:
N-[2-(4-BROMOCINNAMYLAMINO)ETHYL]-5-ISOQUINOLINE SULFONAMIDE / inhibitor*YM

ChemComp-NI:
NICKEL (II) ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / HASPIN / GERM CELL ASSOCIATED 2 / HAPLOID GERM CELL SPECIFIC NUCLEAR PROTEIN KINASE / ATP-BINDING / CELL CYCLE / CHROMATIN REGULATOR / KINASE / MAGNESIUM / NUCLEOTIDE-BINDING / NUCLEUS / PHOSPHOPROTEIN / SERINE/THREONINE-PROTEIN KINASE / STRUCTURAL GENOMICS CONSORTIUM / SGC

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