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TitleHigh-resolution crystal structure of human Mapkap kinase 3 in complex with a high affinity ligand
Journal, issue, pagesProtein Sci., Vol. 19, Page 168-173, Year 2010
Publish dateDec 10, 2008 (structure data deposition date)
AuthorsCheng, R. / Felicetti, B. / Palan, S. / Toogood-Johnson, I. / Scheich, C. / Barker, J. / Whittaker, M. / Hesterkamp, T.
External linksProtein Sci. / PubMed:19937655
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-3fhr:
High resolution crystal structure of mitogen-activated protein kinase-activated protein kinase 3 (MK3)-inhibitor complex
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-P4O:
2-(2-QUINOLIN-3-YLPYRIDIN-4-YL)-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Kinase-inhibitor complex / ATP-binding / Kinase / Nucleotide-binding / Nucleus / Phosphoprotein / Serine/threonine-protein kinase

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