+Search query
-Structure paper
Title | A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases |
---|---|
Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 19, Page 1371-1375, Year 2009 |
Publish date | Dec 4, 2008 (structure data deposition date) |
Authors | Crocetti, L. / Maresca, A. / Temperini, C. / Hall, R.A. / Scozzafava, A. / Muhlschlegel, F.A. / Supuran, C.T. |
External links | Bioorg. Med. Chem. Lett. / PubMed:19186056 |
Methods | X-ray diffraction |
Resolution | 1.81 Å |
Structure data | PDB-3ffp: |
Chemicals | ChemComp-ZN: ChemComp-HG: ChemComp-LC1: ChemComp-BEZ: ChemComp-HOH: |
Source |
|
Keywords | LYASE / carbonic anhydrase / inhibitors / Acetylation / Cytoplasm / Disease mutation / Metal-binding / Polymorphism / Zinc |