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TitleTranscription inactivation through local refolding of the RNA polymerase structure.
Journal, issue, pagesNature, Vol. 457, Page 332-335, Year 2009
Publish dateSep 30, 2008 (structure data deposition date)
AuthorsBelogurov, G.A. / Vassylyeva, M.N. / Sevostyanova, A. / Appleman, J.R. / Xiang, A.X. / Lira, R. / Webber, S.E. / Klyuyev, S. / Nudler, E. / Artsimovitch, I. / Vassylyev, D.G.
External linksNature / PubMed:18946472
MethodsX-ray diffraction
Resolution2.7 Å
Structure data

PDB-3eql:
Crystal structure of the T. Thermophilus RNA polymerase holoenzyme in complex with antibiotic myxopyronin
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-ZN:
Unknown entry

ChemComp-MXP:
Myxopyronin B

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • thermus thermophilus (bacteria)
KeywordsTRANSFERASE / RNA POLYMERASE HOLOENZYME / MYXOPYRONIN / ANTIBIOTIC / TRANSCRIPTION REGULATION / DNA-directed RNA polymerase / Nucleotidyltransferase / Transcription / DNA-binding / Sigma factor

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