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-Structure paper
Title | Synthesis and evaluation of pyrazolo[1,5-b]pyridazines as selective cyclin dependent kinase inhibitors. |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 18, Page 5758-5762, Year 2008 |
Publish date | Sep 15, 2008 (structure data deposition date) |
Authors | Stevens, K.L. / Reno, M.J. / Alberti, J.B. / Price, D.J. / Kane-Carson, L.S. / Knick, V.B. / Shewchuk, L.M. / Hassell, A.M. / Veal, J.M. / Davis, S.T. ...Stevens, K.L. / Reno, M.J. / Alberti, J.B. / Price, D.J. / Kane-Carson, L.S. / Knick, V.B. / Shewchuk, L.M. / Hassell, A.M. / Veal, J.M. / Davis, S.T. / Griffin, R.J. / Peel, M.R. |
External links | Bioorg. Med. Chem. Lett. / PubMed:18835709 |
Methods | X-ray diffraction |
Resolution | 3.15 - 3.22 Å |
Structure data | PDB-3eid: PDB-3ej1: |
Chemicals | ChemComp-PO5: ChemComp-HOH: ChemComp-5BP: |
Source |
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Keywords | Transferase/Cell Cycle / cdk2 / cyclin / ATP-binding / Cell cycle / Cell division / Kinase / Mitosis / Nucleotide-binding / Phosphoprotein / Serine/threonine-protein kinase / Transferase / Nucleus / Transferase-Cell Cycle COMPLEX / cdk |