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TitleIdentification and characterisation of new inhibitors for the human hematopoietic prostaglandin D(2) synthase
Journal, issue, pagesEur. J. Med. Chem., Vol. 45, Page 447-454, Year 2010
Publish dateSep 4, 2008 (structure data deposition date)
AuthorsWeber, J.E. / Oakley, A.J. / Christ, A.N. / Clark, A.G. / Hayes, J.D. / Hall, R. / Hume, D.A. / Board, P.G. / Smythe, M.L. / Flanagan, J.U.
External linksEur. J. Med. Chem. / PubMed:19939518
MethodsX-ray diffraction
Resolution1.91 Å
Structure data

PDB-3ee2:
Structure of human prostaglandin D-synthase (hGSTS1-1) in complex with nocodazole
Method: X-RAY DIFFRACTION / Resolution: 1.91 Å

Chemicals

ChemComp-GSH:
GLUTATHIONE

ChemComp-NZO:
nocodazole / antineoplastic*YM

ChemComp-MG:
Unknown entry

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsISOMERASE / H-PGDS / prostanoid production / inflamation / nocodazole / glutathione transferase sigma / Fatty acid biosynthesis / Lipid synthesis / Prostaglandin biosynthesis

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