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TitleCrystal structure of the Homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex: insights into the molecular basis of kynureninase substrate specificity.
Journal, issue, pagesJ. Med. Chem., Vol. 52, Page 389-396, Year 2009
Publish dateAug 22, 2008 (structure data deposition date)
AuthorsLima, S. / Kumar, S. / Gawandi, V. / Momany, C. / Phillips, R.S.
External linksJ. Med. Chem. / PubMed:19143568
MethodsX-ray diffraction
Resolution1.7 Å
Structure data

PDB-3e9k:
Crystal structure of Homo sapiens kynureninase-3-hydroxyhippuric acid inhibitor complex
Method: X-RAY DIFFRACTION / Resolution: 1.7 Å

Chemicals

ChemComp-PLP:
PYRIDOXAL-5'-PHOSPHATE

ChemComp-3XH:
3-Hydroxyhippuric acid

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / kynureninase / kynurenine-L-hydrolase / kynurenine hydrolase / pyridoxal-5'-phosphate / inhibitor complex / 3-hydroxy hippurate / 3-hydroxyhippuric acid / PLP / Pyridine nucleotide biosynthesis / Pyridoxal phosphate

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