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Structure paper

TitleActivation of RXR-PPAR heterodimers by organotin environmental endocrine disruptors
Journal, issue, pagesEmbo Rep., Vol. 10, Page 367-373, Year 2009
Publish dateAug 21, 2008 (structure data deposition date)
Authorsle Maire, A. / Grimaldi, M. / Roecklin, D. / Dagnino, S. / Vivat-Hannah, V. / Balaguer, P. / Bourguet, W.
External linksEmbo Rep. / PubMed:19270714
MethodsX-ray diffraction
Resolution1.9 Å
Structure data

PDB-3e94:
Crystal structure of RXRalpha ligand binding domain in complex with tributyltin and a coactivator fragment
Method: X-RAY DIFFRACTION / Resolution: 1.9 Å

Chemicals

ChemComp-TBY:
tributylstannanyl

ChemComp-ACT:
ACETATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSCRIPTION / protein-ligand complex / DNA-binding / Host-virus interaction / Metal-binding / Nucleus / Polymorphism / Receptor / Transcription regulation / Ubl conjugation / Zinc / Zinc-finger / Activator / Phosphoprotein

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