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TitleCrystal Structure of Human Haspin with a pyrazolo-pyrimidine ligand
Journal, issue, pagesTo be Published
Publish dateAug 19, 2008 (structure data deposition date)
AuthorsFilippakopoulos, P. / Eswaran, J. / Keates, T. / Burgess-Brown, N. / Fedorov, O. / Pike, A.C.W. / von Delft, F. / Arrowsmith, C.H. / Edwards, A.M. / Wickstroem, M. ...Filippakopoulos, P. / Eswaran, J. / Keates, T. / Burgess-Brown, N. / Fedorov, O. / Pike, A.C.W. / von Delft, F. / Arrowsmith, C.H. / Edwards, A.M. / Wickstroem, M. / Bountra, C. / Knapp, S.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-3e7v:
Crystal Structure of Human Haspin with a pyrazolo-pyrimidine ligand
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-DZO:
3-(3-aminophenyl)-N-(3-chlorophenyl)pyrazolo[1,5-a]pyrimidin-5-amine

ChemComp-NI:
NICKEL (II) ION

ChemComp-EDO:
1,2-ETHANEDIOL

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsTRANSFERASE / Haspin / Germ cell associated 2 (haspin) / Haploid germ cell specific nuclear protein kinase / SGC / structural genomics consortium / ATP-binding / Cell cycle / Chromatin regulator / Kinase / Magnesium / Nucleotide-binding / Nucleus / Phosphoprotein / Serine/threonine-protein kinase

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