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| Title | Structural analysis of spiro beta-lactone proteasome inhibitors. |
|---|---|
| Journal, issue, pages | J. Am. Chem. Soc., Vol. 130, Page 14981-14983, Year 2008 |
| Publish date | Jul 25, 2008 (structure data deposition date) |
Authors | Groll, M. / Balskus, E.P. / Jacobsen, E.N. |
External links | J. Am. Chem. Soc. / PubMed:18928262 |
| Methods | X-ray diffraction |
| Resolution | 2.8 - 2.81 Å |
| Structure data | ![]() PDB-3dy3: ![]() PDB-3dy4: |
| Chemicals | ![]() ChemComp-SLR: ![]() ChemComp-HOH: ![]() ChemComp-SLA: |
| Source |
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Keywords | HYDROLASE / Proteasome / Inhibitor / Protein Degradation / Ubiquitin-Proteasome-Pathway / Cytoplasm / Nucleus / Protease / Threonine protease / Ubl conjugation / Phosphoprotein / Zymogen |
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