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Structure paper

TitleIncorporation of a non-human glycan mediates human susceptibility to a bacterial toxin
Journal, issue, pagesNature, Vol. 456, Page 648-652, Year 2008
Publish dateJul 22, 2008 (structure data deposition date)
AuthorsByres, E. / Paton, A.W. / Paton, J.C. / Lofling, J.C. / Smith, D.F. / Wilce, M.C.J. / Talbot, U.M. / Chong, D.C. / Yu, H. / Huang, S. ...Byres, E. / Paton, A.W. / Paton, J.C. / Lofling, J.C. / Smith, D.F. / Wilce, M.C.J. / Talbot, U.M. / Chong, D.C. / Yu, H. / Huang, S. / Chen, X. / Varki, N.M. / Varki, A. / Rossjohn, J. / Beddoe, T.
External linksNature / PubMed:18971931
MethodsX-ray diffraction
Resolution2.084 - 2.2 Å
Structure data

PDB-3dwa:
Crystal structure of the B-subunit of the AB5 toxin from E. coli
Method: X-RAY DIFFRACTION / Resolution: 2.084 Å

PDB-3dwp:
Crystal structure of the B-subunit of the AB5 toxin from E. Coli with Neu5Gc
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-3dwq:
Crystal structure of the A-subunit of the AB5 toxin from E. coli with Neu5Gc-2,3Gal-1,3GlcNAc
Method: X-RAY DIFFRACTION / Resolution: 2.1 Å

Chemicals

ChemComp-1PE:
PENTAETHYLENE GLYCOL / precipitant*YM

ChemComp-HOH:
WATER

ChemComp-NGC:
N-glycolyl-alpha-neuraminic acid

ChemComp-POL:
N-PROPANOL

ChemComp-AZI:
AZIDE ION

Source
  • escherichia coli (E. coli)
KeywordsTOXIN

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