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-Structure paper
| Title | First Cdc7 kinase inhibitors: pyrrolopyridinones as potent and orally active antitumor agents. 2. Lead discovery. |
|---|---|
| Journal, issue, pages | J. Med. Chem., Vol. 52, Page 293-307, Year 2009 |
| Publish date | Jul 17, 2008 (structure data deposition date) |
 Authors | Menichincheri, M. / Bargiotti, A. / Berthelsen, J. / Bertrand, J.A. / Bossi, R. / Ciavolella, A. / Cirla, A. / Cristiani, C. / Croci, V. / D'Alessio, R. ...Menichincheri, M. / Bargiotti, A. / Berthelsen, J. / Bertrand, J.A. / Bossi, R. / Ciavolella, A. / Cirla, A. / Cristiani, C. / Croci, V. / D'Alessio, R. / Fasolini, M. / Fiorentini, F. / Forte, B. / Isacchi, A. / Martina, K. / Molinari, A. / Montagnoli, A. / Orsini, P. / Orzi, F. / Pesenti, E. / Pezzetta, D. / Pillan, A. / Poggesi, I. / Roletto, F. / Scolaro, A. / Tato, M. / Tibolla, M. / Valsasina, B. / Varasi, M. / Volpi, D. / Santocanale, C. / Vanotti, E. |
 External links | J. Med. Chem. / PubMed:19115845 |
| Methods | X-ray diffraction |
| Resolution | 2.2 Å |
| Structure data |  PDB-3du8: |
| Chemicals |  ChemComp-553:  ChemComp-HOH: |
| Source |
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 Keywords | TRANSFERASE / Protein kinase / Alternative splicing / ATP-binding / Nucleotide-binding / Phosphoprotein / Serine/threonine-protein kinase |
homo sapiens (human)