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Structure paper

TitleStructural constraints imposed by the conserved fusion peptide on the HIV-1 gp41 epitope recognized by the broadly neutralizing antibody 2F5.
Journal, issue, pagesJ. Phys. Chem. B, Vol. 113, Page 13626-13637, Year 2009
Publish dateJul 11, 2008 (structure data deposition date)
Authorsde la Arada, I. / Julien, J.P. / de la Torre, B.G. / Huarte, N. / Andreu, D. / Pai, E.F. / Arrondo, J.L. / Nieva, J.L.
External linksJ. Phys. Chem. B / PubMed:19754136
MethodsX-ray diffraction
Resolution3.3 - 3.6 Å
Structure data

PDB-3drt:
Crystal structure of the HIV-1 broadly neutralizing antibody 2F5 in complex with the gp41 scrambledFP-MPER scrHyb3K construct GIGAFGLLGFLAAGSKK-Ahx-K656NEQELLELDKWASLWN671
Method: X-RAY DIFFRACTION / Resolution: 3.3 Å

PDB-3egs:
Crystal structure of the HIV-1 broadly neutralizing antibody 2F5 in complex with the gp41 scrambledFP-MPER scrHyb3K construct GIGAFGLLGFLAAGSKK-Ahx-K656NEQELLELDKWASLWN671 soaked in ammonium sulfate
Method: X-RAY DIFFRACTION / Resolution: 3.6 Å

Chemicals

ChemComp-GOL:
GLYCEROL

Source
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / HIV-1 / gp41 / 2F5 / nmAb / HIV

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