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-Structure paper
Title | Activation of tyrosine kinases by mutation of the gatekeeper threonine. |
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Journal, issue, pages | Nat. Struct. Mol. Biol., Vol. 15, Page 1109-1118, Year 2008 |
Publish date | Jul 9, 2008 (structure data deposition date) |
Authors | Azam, M. / Seeliger, M.A. / Gray, N.S. / Kuriyan, J. / Daley, G.Q. |
External links | Nat. Struct. Mol. Biol. / PubMed:18794843 |
Methods | X-ray diffraction |
Resolution | 2.017 - 2.3 Å |
Structure data | PDB-3dqw: PDB-3dqx: |
Chemicals | ChemComp-AGS: ChemComp-MG: ChemComp-HOH: ChemComp-AMP: |
Source |
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Keywords | TRANSFERASE / SRC / KINASE / ACTIVE / GATEKEEPER / ATP-binding / Lipoprotein / Myristate / Nucleotide-binding / Phosphoprotein / Proto-oncogene / SH2 domain / SH3 domain / Tyrosine-protein kinase |