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TitleStructural analysis of substrate and effector binding in Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase
Journal, issue, pagesBiochemistry, Vol. 47, Page 8271-8282, Year 2008
Publish dateJun 3, 2008 (structure data deposition date)
AuthorsDey, S. / Burton, R.L. / Grant, G.A. / Sacchettini, J.C.
External linksBiochemistry / PubMed:18627175
MethodsX-ray diffraction
Resolution2.4 - 2.7 Å
Structure data

PDB-3dc2:
Crystal structure of serine bound D-3-phosphoglycerate dehydrogenase from Mycobacterium tuberculosis
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-3ddn:
Crystal structure of hydroxypyruvic acid phosphate bound D-3-phosphoglycerate dehydrogenase in mycobacterium tuberculosis
Method: X-RAY DIFFRACTION / Resolution: 2.4 Å

Chemicals

ChemComp-SER:
SERINE

ChemComp-TLA:
L(+)-TARTARIC ACID

ChemComp-HOH:
WATER

ChemComp-HPV:
2-oxo-3-(phosphonooxy)propanoic acid

Source
  • mycobacterium tuberculosis (bacteria)
KeywordsOXIDOREDUCTASE / PHOSPHOGLYCERATE DEHYDROGENASE / SERINE BIOSYNTHESIS / Amino-acid biosynthesis / NAD

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