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Structure paper

TitleThe crystal structure of avian CD1 reveals a smaller, more primordial antigen-binding pocket compared to mammalian CD1
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 105, Page 17925-17930, Year 2008
Publish dateJun 2, 2008 (structure data deposition date)
AuthorsZajonc, D.M. / Striegl, H. / Dascher, C.C. / Wilson, I.A.
External linksProc. Natl. Acad. Sci. Usa / PubMed:19004781
MethodsX-ray diffraction
Resolution2 Å
Structure data

PDB-3dbx:
Structure of chicken CD1-2 with bound fatty acid
Method: X-RAY DIFFRACTION / Resolution: 2 Å

Chemicals

ChemComp-NAG:
2-acetamido-2-deoxy-beta-D-glucopyranose

ChemComp-PLM:
PALMITIC ACID

ChemComp-HOH:
WATER

Source
  • gallus gallus (chicken)
  • homo sapiens (human)
KeywordsIMMUNE SYSTEM / CD1 / evolution / antigen-presentation / MHC-fold / hydrophobic binding groove / Immunoglobulin domain / Membrane / Transmembrane / Disease mutation / Glycation / Glycoprotein / Immune response / MHC I / Pyrrolidone carboxylic acid / Secreted

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