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Structure paper

TitleThe Structure of the GAF A Domain from Phosphodiesterase 6C Reveals Determinants of cGMP Binding, a Conserved Binding Surface, and a Large cGMP-dependent Conformational Change.
Journal, issue, pagesJ. Biol. Chem., Vol. 283, Page 25913-25919, Year 2008
Publish dateMay 30, 2008 (structure data deposition date)
AuthorsMartinez, S.E. / Heikaus, C.C. / Klevit, R.E. / Beavo, J.A.
External linksJ. Biol. Chem. / PubMed:18614542
MethodsX-ray diffraction
Resolution2.57 Å
Structure data

PDB-3dba:
Crystal structure of the cGMP-bound GAF a domain from the photoreceptor phosphodiesterase 6C
Method: X-RAY DIFFRACTION / Resolution: 2.57 Å

Chemicals

ChemComp-35G:
GUANOSINE-3',5'-MONOPHOSPHATE

ChemComp-GOL:
GLYCEROL

ChemComp-HOH:
WATER

Source
  • gallus gallus (chicken)
KeywordsHYDROLASE / 3' / 5' cGMP / GAF domain / cyclic nucleotide phosphodiesterase / cGMP / Lipoprotein / Membrane / Prenylation / Sensory transduction / Vision

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