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TitleA genetically encoded diazirine photocrosslinker in Escherichia coli
Journal, issue, pagesChemBioChem, Vol. 8, Page 2210-2214, Year 2007
Publish dateMay 20, 2008 (structure data deposition date)
AuthorsTippmann, E. / Liu, W. / Summerer, D. / Mack, A.V. / Schultz, P.G.
External linksChemBioChem / PubMed:18000916
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-3d6u:
Crystal structure of 4-(trifluoromethyldiazirinyl)phenylalanyl-tRNA synthetase
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

PDB-3d6v:
Crystal structure of 4-(trifluoromethyldiazirinyl)phenylalanyl-tRNA synthetase
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-T11:
4-[3-(TRIFLUOROMETHYL)DIAZIRIDIN-3-YL]-L-PHENYLALANINE

ChemComp-BME:
BETA-MERCAPTOETHANOL

ChemComp-HOH:
WATER

ChemComp-TFQ:
4-(2,2,2-TRIFLUOROETHYL)-L-PHENYLALANINE

Source
  • methanocaldococcus jannaschii (archaea)
KeywordsLIGASE / photocrosslinking Unnatural amino acid / Aminoacyl-tRNA synthetase / ATP-binding / Cytoplasm / Nucleotide-binding / Protein biosynthesis

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