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-Structure paper
Title | Synthesis and structure based optimization of novel Akt inhibitors |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 18, Page 3359-3363, Year 2008 |
Publish date | Apr 3, 2008 (structure data deposition date) |
![]() | Lippa, B. / Pan, G. / Corbett, M. / Li, C. / Kauffman, G.S. / Pandit, J. / Robinson, S. / Wei, L. / Kozina, E. / Marr, E.S. ...Lippa, B. / Pan, G. / Corbett, M. / Li, C. / Kauffman, G.S. / Pandit, J. / Robinson, S. / Wei, L. / Kozina, E. / Marr, E.S. / Borzillo, G. / Knauth, E. / Barbacci-Tobin, E.G. / Vincent, P. / Troutman, M. / Baker, D. / Rajamohan, F. / Kakar, S. / Clark, T. / Morris, J. |
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Methods | X-ray diffraction |
Resolution | 2 - 2.2 Å |
Structure data | ![]() PDB-3cqu: ![]() PDB-3cqw: |
Chemicals | ![]() ChemComp-CQU: ![]() ChemComp-HOH: ![]() ChemComp-MN: ![]() ChemComp-CQW: |
Source |
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![]() | TRANSFERASE / Kinase / Apoptosis / ATP-binding / Carbohydrate metabolism / Cytoplasm / Glucose metabolism / Glycogen biosynthesis / Glycogen metabolism / Membrane / Nucleotide-binding / Nucleus / Phosphoprotein / Serine/threonine-protein kinase / Sugar transport / Translation regulation / Transport / Alternative splicing / Wnt signaling pathway |