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Structure paper

Titlecis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects.
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 105, Page 8902-8907, Year 2008
Publish dateMar 27, 2008 (structure data deposition date)
AuthorsLovejoy, K.S. / Todd, R.C. / Zhang, S. / McCormick, M.S. / D'Aquino, J.A. / Reardon, J.T. / Sancar, A. / Giacomini, K.M. / Lippard, S.J.
External linksProc. Natl. Acad. Sci. Usa / PubMed:18579768
MethodsX-ray diffraction
Resolution2.16 Å
Structure data

PDB-3co3:
X-Ray Crystal Structure of a Monofunctional Platinum-DNA Adduct, cis-{Pt(NH3)2(pyridine)}2+ Bound to Deoxyguanosine in a Dodecamer Duplex
Method: X-RAY DIFFRACTION / Resolution: 2.16 Å

Chemicals

ChemComp-C7P:
cis-diammine(pyridine)chloroplatinum(II)

ChemComp-HOH:
WATER

KeywordsDNA / PLATINUM-DNA DUPLEX / CISPLATIN / MONOFUNCTIONAL PT COMPOUND

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