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-Structure paper
Title | Pyridine amides as potent and selective inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 |
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Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 18, Page 3168-3172, Year 2008 |
Publish date | Mar 7, 2008 (structure data deposition date) |
![]() | Wang, H. / Ruan, Z. / Li, J.J. / Simpkins, L.M. / Smirk, R.A. / Wu, S.C. / Hutchins, R.D. / Nirschl, D.S. / Van Kirk, K. / Cooper, C.B. ...Wang, H. / Ruan, Z. / Li, J.J. / Simpkins, L.M. / Smirk, R.A. / Wu, S.C. / Hutchins, R.D. / Nirschl, D.S. / Van Kirk, K. / Cooper, C.B. / Sutton, J.C. / Ma, Z. / Golla, R. / Seethala, R. / Salyan, M.E. / Nayeem, A. / Krystek, S.R. / Sheriff, S. / Camac, D.M. / Morin, P.E. / Carpenter, B. / Robl, J.A. / Zahler, R. / Gordon, D.A. / Hamann, L.G. |
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Methods | X-ray diffraction |
Resolution | 2.35 Å |
Structure data | ![]() PDB-3ch6: |
Chemicals | ![]() ChemComp-NAP: ![]() ChemComp-311: ![]() ChemComp-HOH: |
Source |
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![]() | OXIDOREDUCTASE / 11B-HSD1 / sdr / dehydrogenase / hydroxysteroid / inhibitor |