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Structure paper

TitleSmall-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling.
Journal, issue, pagesProc. Natl. Acad. Sci. Usa, Vol. 105, Page 5632-5637, Year 2008
Publish dateFeb 4, 2008 (structure data deposition date)
AuthorsHayashi, K. / Tan, X. / Zheng, N. / Hatate, T. / Kimura, Y. / Kepinski, S. / Nozaki, H.
External linksProc. Natl. Acad. Sci. Usa / PubMed:18391211
MethodsX-ray diffraction
Resolution2.6 - 2.7 Å
Structure data

PDB-3c6n:
Small molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling
Method: X-RAY DIFFRACTION / Resolution: 2.6 Å

PDB-3c6o:
Small molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

PDB-3c6p:
Small molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling
Method: X-RAY DIFFRACTION / Resolution: 2.7 Å

Chemicals

ChemComp-IHP:
INOSITOL HEXAKISPHOSPHATE

ChemComp-2S8:
(2S)-8-[(tert-butoxycarbonyl)amino]-2-(1H-indol-3-yl)octanoic acid

ChemComp-HOH:
WATER

ChemComp-2S2:
(2S)-2-(1H-indol-3-yl)hexanoic acid

ChemComp-2S3:
(2S)-2-(1H-indol-3-yl)pentanoic acid

Source
  • arabidopsis thaliana (thale cress)
KeywordsSIGNALING PROTEIN / Auxin / ubiquitin ligase / small molecules / plant physiology / chemical biology / Auxin signaling pathway / Chromosome partition / Cytoplasm / Cytoskeleton / Developmental protein / Ethylene signaling pathway / Nucleus / Ubl conjugation pathway / Cell cycle / Leucine-rich repeat / Plant defense / F-box / small molecule

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