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TitleLyp/PTPN22 Phosphatase Domain: Substrate Recognition and Specificity for Src family kinases
Journal, issue, pagesTo be Published
Publish dateDec 21, 2007 (structure data deposition date)
AuthorsSeidel, R. / Love, J. / Piserchio, A. / Cowburn, D.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution2.2 Å
Structure data

PDB-3brh:
Protein Tyrosine Phosphatase PTPN-22 (Lyp) bound to the mono-Phosphorylated Lck active site peptide
Method: X-RAY DIFFRACTION / Resolution: 2.2 Å

Chemicals

ChemComp-PO4:
PHOSPHATE ION

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / Lyp / PTPN22 / phosphatase / Lck / Alternative splicing / Cytoplasm / Polymorphism / Protein phosphatase / Systemic lupus erythematosus

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