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Structure paper

TitleCrystal structure of human beta-hydroxyisobutyryl-CoA hydrolase in complex with quercetin.
Journal, issue, pagesTo be Published
Publish dateDec 19, 2007 (structure data deposition date)
AuthorsPilka, E.S. / Phillips, C. / King, O.N.F. / Guo, K. / von Delft, F. / Pike, A.C.W. / Arrowsmith, C.H. / Weigelt, J. / Edwards, A.M. / Oppermann, U.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.5 Å
Structure data

PDB-3bpt:
Crystal structure of human beta-hydroxyisobutyryl-CoA hydrolase in complex with quercetin
Method: X-RAY DIFFRACTION / Resolution: 1.5 Å

Chemicals

ChemComp-QUE:
3,5,7,3',4'-PENTAHYDROXYFLAVONE

ChemComp-HIU:
(2R)-3-HYDROXY-2-METHYLPROPANOIC ACID

ChemComp-HOH:
WATER

Source
  • homo sapiens (human)
KeywordsHYDROLASE / COENZYME A / BETA-HYDROXYISOBUTYRYL ACID / QUERCETIN / STRUCTURAL GENOMICS CONSORTIUM / SGC / Branched-chain amino acid catabolism / Disease mutation / Mitochondrion / Transit peptide

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