+Search query
-Structure paper
Title | Carbonic anhydrase inhibitors. Interaction of indapamide and related diuretics with 12 mammalian isozymes and X-ray crystallographic studies for the indapamide-isozyme II adduct. |
---|---|
Journal, issue, pages | Bioorg. Med. Chem. Lett., Vol. 18, Page 2567-2573, Year 2008 |
Publish date | Dec 10, 2007 (structure data deposition date) |
Authors | Temperini, C. / Cecchi, A. / Scozzafava, A. / Supuran, C.T. |
External links | Bioorg. Med. Chem. Lett. / PubMed:18374572 |
Methods | X-ray diffraction |
Resolution | 2.1 Å |
Structure data | PDB-3bl1: |
Chemicals | ChemComp-ZN: ChemComp-HG: ChemComp-BL1: ChemComp-HOH: |
Source |
|
Keywords | LYASE / carbonic anhydrase / inhibitors / diuretics / Acetylation / Cytoplasm / Disease mutation / Metal-binding / Polymorphism / Zinc / LYASE(OXO-ACID) |