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TitleA new generation of specific Trypanosoma cruzi trans-sialidase inhibitors.
Journal, issue, pagesAngew. Chem. Int. Ed. Engl., Vol. 47, Page 2700-2703, Year 2008
Publish dateOct 28, 2007 (structure data deposition date)
AuthorsBuchini, S. / Buschiazzo, A. / Withers, S.G.
External linksAngew. Chem. Int. Ed. Engl. / PubMed:18300214
MethodsX-ray diffraction
Resolution1.67 Å
Structure data

PDB-3b69:
T cruzi Trans-sialidase complex with benzoylated NANA derivative
Method: X-RAY DIFFRACTION / Resolution: 1.67 Å

Chemicals

ChemComp-CL:
Unknown entry

ChemComp-BFN:
5-acetamido-9-(benzoylamino)-3,5,9-trideoxy-3-fluoro-D-erythro-alpha-L-manno-non-2-ulopyranosonic acid

ChemComp-EPE:
4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID / pH buffer*YM

ChemComp-HOH:
WATER

Source
  • trypanosoma cruzi (eukaryote)
KeywordsHYDROLASE / beta-propeller

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