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-Structure paper
Title | Structural basis for EGF receptor inhibition by the therapeutic antibody IMC-11F8. |
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Journal, issue, pages | Structure, Vol. 16, Page 216-227, Year 2008 |
Publish date | Oct 19, 2007 (structure data deposition date) |
![]() | Li, S. / Kussie, P. / Ferguson, K.M. |
![]() | ![]() ![]() |
Methods | X-ray diffraction |
Resolution | 2.58 - 3.3 Å |
Structure data | ![]() PDB-3b2u: ![]() PDB-3b2v: |
Chemicals | ![]() ChemComp-NAG: ![]() ChemComp-SO4: ![]() ChemComp-HOH: |
Source |
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![]() | IMMUNE SYSTEM/TRANSFERASE / CELL SURFACE RECEPTOR; GLYCOPROTEIN; ANTIGEN:ANTIBODY COMPLEX; FAB FRAGMENT; ANTITUMOR; DRUG / Anti-oncogene / ATP-binding / Cell cycle / Disease mutation / Kinase / Membrane / Nucleotide-binding / Phosphoprotein / Secreted / Transferase / Transmembrane / Tyrosine-protein kinase / IMMUNE SYSTEM-TRANSFERASE COMPLEX |