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TitleStructural insight into kynurenic acid excretion mechanisms of kynurenine aminotransferase in the hyperthermophilic archaeon Pyrococcus horikoshii
Journal, issue, pagesTo be Published
Publish dateFeb 23, 2011 (structure data deposition date)
AuthorsOkada, K. / Angkawidjaja, C. / Koga, Y. / Takano, K. / Kanaya, Y.
External linksSearch PubMed
MethodsX-ray diffraction
Resolution1.84 Å
Structure data

PDB-3av7:
Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with PMP, KYN as substrates and KYA as products
Method: X-RAY DIFFRACTION / Resolution: 1.84 Å

Chemicals

ChemComp-PMP:
4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE

ChemComp-KYN:
(2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid

ChemComp-KYA:
4-hydroxyquinoline-2-carboxylic acid

ChemComp-HOH:
WATER

Source
  • pyrococcus horikoshii (archaea)
KeywordsTRANSFERASE / aminotransferase / PLP binding / transamination

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